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Binding of AngII to its AT1 receptor leads to the activation of MAP kinases, phosphorylation of tyrosine kinases and production of ROS, all of which induce VSMC proliferation

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When to Use Z86.79 Instead of R55 Z86.79 (Personal history of other diseases of the circulatory system) is the appropriate code when: Patient is being seen for a different condition but has a history of syncope that affects clinical decision-making Pre-operative assessment notes prior syncopal episodes Cardiologist sees patient for follow-up after syncope workup was completed and no current symptoms Patient presents for unrelated complaint and mentions "I had a fainting spell a few months ago"