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Furthermore, the authors indicated that, upon comparison with the literature, the effective concentration was sufficiently low to suggest a signaling role for Epitalon in the cascades of the cellular antioxidant system [57]
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4,7 The link between hearing loss and tinnitus has been suggested to be due to a compensatory effect: the brain compensates for decreased activation of the auditory nerve (which carries signals from the cochlea to the brain) by increasing “gain” or signal amplification in the auditory system of the brain, as well as decreasing auditory signal inhibition, which may result in tinnitus and possibly hypersensitivity to noise
