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Furthermore, interventional studies in DSS-colitis suggest targeting ferroptosis could be therapeutic: β-caryophyllene inhibition of macrophage lipid peroxidation and ferroptosis was linked to suppression of inflammation [12], and seliciclib-treated mice—that displayed reduced epithelial ferroptosis—had less severe DSS-induced colitis [41]
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[DOI] [PMC free article] [PubMed] [Google Scholar] 217.Ye J, et al
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