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IBS is also associated with fungal microbiota imbalance, especially overgrowth of Candida ( Akkermansia muciniphila can exacerbate the colonization of Candida tropicalis ( Escherichia coli in the gut significantly affects the hyphae and biofilms formation of Candida , and upregulates pathogenic genes such as ALS3 and HWP1 ( Escherichia coli is associated with the occurrence of Crohn’s disease, and it can promote the hyphae invasion of Candida into intestinal epithelium and lamina propria through the ability to destroy and invade epithelial cells and trigger intestinal inflammation (Zhilu et al., 2021

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This study shows that MYC-mediated transformation drives glutamine into biosynthetic pathways