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41 This requirement of eosinophils is site specific, as Th2 priming is unaffected with immunization in areas normally devoid of eosinophils such as peritoneum, skin, or rectum

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On the other hand, the inverse association of riboflavin with plasma homocysteine levels can also be attributed to riboflavin’s interaction with methyltetrahydrofolate reductase (MTHFR), another peculiar flavoprotein involved in follicular activity, embryo quality and pregnancy success 90,91,92