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It acts as a selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme expressed in multiple tissues — including adipose tissue and the liver — that plays a role in cellular energy metabolism and fat storage

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Complementary genetic screens identify vitamin B 12 as a key alleviator of rnp-6(G281D) phenotypes Utilizing the cpbl-1 reporter strain, we performed a two-way genetic screen to identify K12-type E