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Simultaneously, the activated PI3K/Akt pathway promotes cell survival through effects on key pro-apoptotic proteins, including BAD, while the PLC-γ pathway activates cytoskeletal change related to neurite outgrowth by mobilizing intracellular calcium [45]

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This process removes water at a low temperature, which preserves the delicate peptide bonds and tertiary structure, keeping it stable for long-term storage

The ratio of glutathione reduced (GSH) to glutathione oxidized (GSSG) determines the cell’s redox status