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Then, the cells were treated with different concentrations (100, 50, 25, 12.5, 6.25, and 3.125 μg/mL) of Ag-MSNs@CHX or Ag-MSNs, whereas the free drugs were dosed assuming 20% CHX loading (20, 10, 5, 2.5, 1.25, 0.625 μg/mL)