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Using confocal microscopy, we observed that USAG-1 was predominantly localized in the cytoplasm of HK-2 cells, with minimal nuclear presence (Supplementary Fig

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Donor cells are well known to secrete pro-survival, neurotrophic, and pro-myelinating factors that can enhance the proliferation, survival, and differentiation of host OPCs, thereby improving the overall capacity for endogenous myelination and remyelination (Einstein et al., 2009)