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Key variables in study design include: Route of Administration: Will the compound be studied via systemic injection (subcutaneous, intramuscular) or a more localized injection near the site of injury

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It was revealed that NUMA1 interacted with GSTP1-1 and TRAF2, promoted the association of TRAF2 with GSTP1, and inhibited the interaction of TRAF2 and ASK1, regulating the sustained activation of JNK [226]