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Acute toxicity An oral up and down procedure (UDP) was used to determine median lethal dose (LD 50 ) and one animal was tested at a time, and the response of each animal to a test substance determines whether the next animal receives a higher or lower dose

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No growth-hormone effects The fragment keeps the fat-mobilizing tail of human growth hormone but drops the parts that drive blood sugar, IGF-1, or tissue overgrowth in research models