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Similar observations were made in MDA-T32 and MDA-T68 PTC cell lines (Shown in Supplemental Fig
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Lot #:Lot #: N9DSIP10/0729
But significant decrease in mRNA expression of tumor necrosis factor TNF-α and inducible nitric oxide synthase level by 1 µM, 5 µM and 10 µM of Si in sodium metasilicate form and also suppression of cyclooxygenase-2 mRNA expression by 1 µM, 5 µM and 25 µM of Si in the same chemical form suggest ability of silicon to regulate the inflammatory process ( in vitro studies, a reduction in the level of tumor necrosis factor TNF-α in response to low concentrations of silicon and found by Gonzalez-Munoz et al
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