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Frontiers | Monoclonal anti-CD38 therapy in human myeloma: retrospects and prospects

This dual action, increasing fat breakdown while simultaneously reducing new fat formation, has been observed in multiple rodent adipocyte models and provides a mechanistically distinct experimental profile compared to compounds that affect only one arm of fat metabolism

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By adding B12, this formulation helps counteract potential fatigue, a common side effect of reduced food intake, ensuring sustained energy levels throughout treatment