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This depends on the dose and vial size: 100mg vial at 50mg/dose = 2 doses 100mg vial at 100mg/dose = 1 dose 250mg vial at 50mg/dose = 5 doses 250mg vial at 100mg/dose = 2.5 doses 500mg vial at 50mg/dose = 10 doses 500mg vial at 100mg/dose = 5 doses 500mg vial at 200mg/dose = 2.5 doses Community protocols commonly documenting 100mg three times weekly would exhaust a 250mg vial in under a week

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In the bones of the face and skull, the burgeoning marrow erodes existing cortical bone and induces new bone formation, giving rise to a “crewcut” appearance on radiographic studies ( Fig