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PL BioScience has advanced an oral BPC-157 formulation (designated PL-10) to Phase II clinical trials for inflammatory bowel disease — representing the most clinically advanced human development of oral BPC-157 to date.3 Human peer-reviewed results from these trials are pending, but the preclinical rationale is strong

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In addition, flow cytometry analysis showed that knockdown of VDAC1 led to increased ROS levels in PTX-resistant cells ( Figure S2G )