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1μg of total RNA for each sample was used for poly(A) RNA selection using magnetic beads coated with poly-dT, followed by thermal fragmentation

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Because a high percentage of people have genetic differences that inhibit the activation of B vitamins (called MTHFR genetic mutations), the best versions of these vitamins to take are the already-activated, "methylated" forms: methylfolate, methylcobalamin, hydroxy- or hydroxocobalamin, or adenosylcobalamin