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Manufactured in Japan by Mitsubishi Corporation Life Sciences Limited/Mitsubishi International Food Ingredients, Inc., OPITAC™ GSH is FDA-notified GRAS, certified Halal, Kosher, and has achieved both USP and JP monograph designations, along with GMP approval by the Japanese government

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In Phase 2, 41–63% of cagrilintide participants reported GI events versus 32% on placebo, with nausea the leading complaint