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All those helminth-induced effects are, in the majority, associated with the antigens actively released – ES – or shed from a tegument by the worms (Surface Antigens – SA) ( + Tregs (281), CD8 + Tregs (282), and regulatory B cells (283), as well as the production of TGF-β, IL-10, and Th2 cytokines (284, 285)

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Figure 6 10 Replacing antibiotics with probiotics and prebiotics in aquaculture The mismanagement of antibiotics in aquaculture poses a grave concern with widespread impacts (Hemamalini et al., 2022)