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5-Amino-1MQ — formally 5-amino-1-methylquinolinium iodide — is a small-molecule selective inhibitor of nicotinamide N-methyltransferase (NNMT)

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Earlier generations, including MZ-, JV-1-, and JMR-series antagonists, showed efficacy in endometrial 74 , renal 75 , lung 76,77,78 , glioblastoma 79 , breast 80 , and colon cancers 79