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Clinical and in vivo PD studies using repurposed anti-diabetic medications report mixed results but suggest an overall potential modest benefit (50) in motor and cognitive symptoms with GLP-1 receptor agonists taken for at least 12 months (51)
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For instance, adipocytes promote GC omental metastasis via phosphatidylinositol transfer protein, cytoplasmic 1 (PITPNC1)-mediated fatty acid metabolic reprogramming (Tan et al., 2018)
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