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In fact, it is now known that the -SH group indeed oxidizes during sample acidification, probably as the consequence of the release of reactive oxygen species from the biological matrices
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Immunoreactivity for mGlu 8 has been identified particularly in small DRG neurons that are TRPV1-positive and thus may be predominantly peptidergic C-fibre nociceptors ( Our studies do not provide direct insights into the precise location of the mGlu 2 and mGlu 8 receptors here, other than to indicate selective impact on first relay synapses from non-peptidergic and peptidergic afferents
