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Immunofluorescence staining and western blot results verified that GPX1 expression was absent in the cochlear SGNs of gpx1 –/– mice (Supplementary Figures 1A,C), and there was no significant difference in SGNs number between the gpx1 –/– mice and WT mice (Supplementary Figure 1B), which indicated that the absence of GPX1 in normal SGNs would not affect the survival of SGNs

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A complete evaluation of adrenal function should consider clinical presentation and molecular markers to ensure timely diagnosis and management of relative adrenal insufficiency in ACLD patients[50-61]

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