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Short Hairpin RNA A target sequence for c-Met was designed using RNAi central design program ( The target sequence GTGTCAGGAGGTGTTTGGAAAG was inserted into pSUPER vector (Oligoengine, Seattle, WA), which drives endogenous production of short hairpin RNA (shRNA) under the H1 promoter

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In addition, the Aβ production was reduced by using an antioxidant, NAC