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GHK is known to work as an anti-inflammatory and antioxidant agent by decreasing inflammatory cytokines and reducing reactive oxygen species (ROS) levels [7]

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410 Berberine also alleviates DR by inhibiting insulin-induced activation of retinal ECs through the Akt/mTOR/HIF-1α/VEGF pathway 411 and reduces DCM by suppressing IL-1β secretion and gasdermin D expression

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