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In cultured dermal fibroblasts and ex-vivo skin models, GHK-Cu has been reported to modulate the expression of extracellular-matrix proteins (collagens, decorin), influence transforming growth factor-β (TGF-β) signalling, and act as an antioxidant via the copper-cycling redox activity

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[DOI] [PMC free article] [PubMed] [Google Scholar] 194.Liu J., Xie L., Zhai H., Wang D., Li X., Wang Y., Song M., Xu C