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In EGT-producing cyanobacteria, which necessarily possess all EGT-synthesis genes, egtB , egtC and egtD , but not egtE , have been identified by sequence homology with their mycobacterial orthologs [171], and we have observed in the model species Synechocystis PCC 6803 that it is GSH itself, not its γ-Glu-Cys precursor, that serves for EGT synthesis [61]