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The exact temporal coincidence of changes in follicle size, cutaneous (but not epidermal) thickness, and perifollicular vascularization suggested that the angiogenic stimulus was derived from either the hair follicle itself or the surrounding dermis and subcutis, but not from the interfollicular epidermis

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For example, vitamin B3 (niacin) serves as a primary building block, while tryptophan, an amino acid, offers an alternative pathway for NAD+ synthesis through the kynurenine process