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For this purpose, oxidative stress biomarkers, such as advanced glycation end products (AGEs), oxidized low-density lipoprotein (oxLDL), lipid oxidation products, trans-4-hydroxy-2-nonenal (4-HNE), MDA, F 2 -isoprostanes (F 2 -IsoPs) or similar isolevuglandins (IsoLGs), are used, as they reflect the action of ROS in biological systems

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Vitamin B : Vitamin B 6 deficiency 6 (pyridoxine) is required for hemoglobin production, being a cofactor for delta-ALA synthetase, the first and rate-limiting step in the heme synthesis pathway