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Based on these data, the FDA approved tesamorelin (marketed as EGRIFTA) for the reduction of excess abdominal fat in HIV‑associated lipodystrophy, not as a general weight‑loss drug for the wider population. Tesamorelin Risks and Considerations Like all hormone‑modulating therapies, tesamorelin carries potential risks, including fluid retention, joint pain, injection‑site reactions, and effects on glucose metabolism in susceptible patients
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