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Glutaminase is crucial for glutamine dependency in ibrutinib-resistant mantle cell lymphoma cells To understand the role of GLS in contributing to glutamine dependency and ibrutinib resistance, we generated MCL cells with stable GLS overexpression from ibrutinib-sensitive JeKo-1 and Rec-1 cells (Figure 3A, Online Supplementary Figure S2A )

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This preparation method helps improve stability during shipping and storage