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The levels of pro-inflammatory chemokines (MIP-1α, MIP-1β, RANTES) secreted by activated DC, macrophages and endothelial cells and recognized by CCR5 increase in the aging thymus, just like intrathymic lipid-laden multilocular and adipose cells (LLC), whose number is inversely related with thymic function [76]
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Simons CL, Malone D, Wang M , Maglinte GA, Inocencio T, Wade SW, Bennison C, Shah B
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