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Additionally, while some clinical guidelines and reviews have cautiously recommended checking vitamin D levels in children with ASD (given the high rates of deficiency), our review provides a stronger evidence base for such practices by demonstrating the consistency and magnitude of the deficiency across studies, and by showing that correcting it has tangible, if modest, benefits

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Identification of CYP3A4 and CYP2C8 as the major cytochrome P450 s responsible for morphine N –demethylation in human liver microsomes