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Most of these PSD-95 positive spines are stable, but, in the rare cases that they lose PSD-95 and disappear, or are formed de novo and gain PSD-95, their dynamics result in a persistent synapse gain or loss and permanent circuit rewiring associated with learning and memory, respectively
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Dihexa(PNB-0408)( 0.1 µM) combining Vitamin C, and Forskolin (VDF) could substitute growth factors to induce hepatic specification [4]
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