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The peptide's plasma half-life is approximately 15 minutes (Graf & Kastin, Neurosci Biobehav Rev, 1984

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It needs to be emphasized that TBI is a pro-inflammatory condition that affects not only the brain, but also impairs functions of other organs including eyes, lung, intestines, myocardium, and vascular circulation with long lasting effects and complications which need to be considered in medical practice [23]