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🔸Mechanism of Action: Dutasteride is a 5-alpha reductase inhibitor, which inhibits the conversion of testosterone to the more active metabolite 5α-dihydrotestosterone (DHT).
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Interestingly, CD8 + T cells compensatory upregulate the Gln transporter ATB + /SLC6A14 to maintain their Gln uptake requirement after treatment with V-9302, but this phenomenon was not observed in tumor cells
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