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To advance the field toward "precision hepatology," future research must address several critical frontiers: Future studies should utilize Mendelian randomization, prospective longitudinal cohorts, and multi-omics integration combined with advanced spatiotemporal technologies

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In addition to GAPDH’s role in viral infection, it is a major suspect in several neurodegenerative diseases in humans, including Huntington’s, Parkinson’s, and Alzheimer’s diseases (88)