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BPC 157 induced the release of the NO on its own [124,125] also in the conditions where L-arginine is not working, i.e., release resistant to L-NAME, inhibiting that NO-over-release by L-arginine [124,125]
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The above studies suggest bioavailability of systemically administered NAC in therapeutic concentrations after experimental TBI, likely facilitated by a disrupted BBB after trauma
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