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Computational investigation of sphingosine kinase 1 (SphK1) and calcium dependent ERK1/2 activation downstream of VEGFR2 in endothelial cells

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In addition, since glutamate taken back up into neurons may be available for re-use as a neurotransmitter, reduced reuptake might also lead to a requirement for enhanced synthesis, and consequently to an increase in whole-tissue glutamate