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By inhibiting NNMT, 5-Amino 1MQ preserves the intracellular NAM pool, shunting it back into the NAD+ salvage pathway and significantly increasing intracellular NAD+ levels

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Two other trials, STEP, which studies the effects of semaglutide in patients with obesity, and SELECT, which investigates the cardiovascular effects of semaglutide in patients with obesity are currently underway (123)