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The 22.8% weight loss and 81.4% liver fat reduction at this dose captures nearly all the benefit of the 12mg tier with meaningfully fewer side effects

NO cyanide

Specification:5 mg vial

In some embodiments, preparation of certain cations of the invention may occur via oxidation of quinoline (using e.g., mCPBA) followed by nitration and chlorination, respectively and further followed by amination and alkylation, respectively, as exemplified with the preparation of cation 2k (Scheme 4)