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A 2018 review in the International Journal of Molecular Sciences compiled the regenerative-research findings against the backdrop of transcriptomic profiling that flagged thousands of human genes as up- or down-regulated under GHK-Cu exposure (PMID 29986520)

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The best results were obtained in the adjuvant to surgery group and in the trans-surgical group (93% and 91% complete response [CR], respectively), followed by the single therapy group (80% CR), and finally, the relapse group, where ECT was applied after local recurrence, at the site where the surgery was perforMed