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Case reports also describe severe cholestatic liver injury linked to recreational RAD-140 use → Cardiovascular Concerns The FDA has warned that SARMs like RAD-140 may increase the risk of heart attack and stroke, in addition to causing liver toxicity → Anti-Doping Status RAD-140 is classified as a prohibited anabolic agent by the World Anti-Doping Agency (WADA) and is banned at all times in sport Side Effects of Ostarine (MK-2866 / Enobosarm) → Clinical Tolerability In clinical trials, Ostarine demonstrated increases in lean mass and improved function with a generally good safety profile → Liver Injury Cases Despite its clinical background, Ostarine has been linked to cholestatic liver injury in case reports, showing it is not free of hepatotoxic risk → Cardiovascular Concerns The FDA has issued consumer alerts that SARMs like Ostarine may cause liver toxicity and increased risks of heart attack and stroke → Anti-Doping Status Like RAD-140, Ostarine is explicitly banned for competitive athletes under the WADA Prohibited List Zilbermint, Mihail F., and Adrian S