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That DSIP was one of only two candidates to survive this decades-long search and reach full characterisation is part of why it attracted such sustained scientific interest despite the small scale of the human trials that followed — though, as detailed throughout this article, being one of the few characterised candidates is not the same as having its role definitively confirmed

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A decline in the expression of TLR4, IL-6, IL-1β, NF-κB, and many other pro-inflammatory signaling molecules, was detected using qPCR, hence demonstrating the anti-inflammatory effects of A