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Notably, incubating peripheral whole blood cultures with vitamin B12 resulted in the normalization of CCL11 expression, the increase of the neuroprotective HGF and the decrease CSF2 and CXCL10 mRNA levels in leukocytes from individuals with persistent VCD (Fig

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Whilst some studies found beneficial effects in patients with AD 36 and dementia 90 and in shift workers, 91 others found no improvements in patients with sleep−wake rhythm disorders