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Abbreviations used AD Alzheimer's disease COX cyclo-oxygenase CVB3 coxsackie virus B3 DIO iodothyronine deiodinase 15d-PGJ 2 15-deoxy-Δ 12,14 -prostaglandin J 2 EFsec selenocysteine tRNA-specific elongation factor ER endoplasmic reticulum GPX glutathione peroxidase I κ B inhibitor of NF- κ B IKK β I κ B kinase β IL-1 β interleukin 1 β IL-2R interleukin 2 receptor LDL low-density lipoprotein NF- κ B nuclear factor κ B NPC Nutritional Prevention of Cancer PACAP pituitary adenylate cyclase-activating polypeptide PD Parkinson's disease PTZ pentylentetrazol ROS reactive oxygen species SBP2 selenocysteine insertion sequence-binding protein 2 Sec selenocysteine SECIS selenocysteine insertion sequence SELECT Selenium and Vitamin E Cancer Prevention Trial SelH (etc.) selenoprotein H (etc.) Sep15 15 kDa selenoprotein SIRS systemic inflammatory response syndrome SPS selenophosphate synthetase SR sarcoplasmic reticulum SRE selenium-response element Tat transactivator of transcription TCR T-cell receptor TNF α tumour necrosis factor α TPM Topiramate tRNA Sec selenocysteine tRNA TRX thioredoxin TRXR thioredoxin reductase UTR untranslated region VCP valosin-containing protein REFERENCES 1.Small-Howard AL, Berry MJ