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In horses, several types of arthritis can occur, with causes ranging from infection to age and years of athletic use.1 Generally, horse owners and others tend to use the word “arthritis” in lieu of osteoarthritis, which is a chronic, progressive, painful degeneration of the cartilage lining the ends of long bones inside joints, as well as the underlying bone and soft tissues

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Remarkably, p16 INK4A and p19 ARF expression were significantly reduced by 70% (Fig