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Copper changes the conversation. GHK-Cu pairs the Gly-His-Lys tripeptide with Cu²⁺ through coordination chemistry. In peptide biochemistry, this makes it a useful classroom example for studying how metal-binding motifs can influence extracellular

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However, when GBM cells were exposed to glucose-deficient conditions, they shifted their metabolism to mitochondrial OXPHOS, increasing mitochondrial translation products