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Specifically, using an in situ approach to measure H 2 O 2 release from mitochondria in permeabilized rat muscle fiber bundles, research reveals that compared to type I fibers, mitochondrial ROS emission (i.e., H 2 O 2 release/O 2 consumed) was two to three fold greater in type II fibers (16)

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10.3233/JAD-2012-112114 J