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Topical application of TRF (5 mg/cm 2 ) on depilated dorsal skin of healthy or diabetic mice markedly induced epidermal hair follicle development and early anagen induction, as evidenced by change of skin color from pink to black

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That preservative is what makes it the default choice for multi-dose research vials a solution reconstituted with bacteriostatic water can typically be accessed multiple times over its usable window without the same contamination risk that a preservative-free solvent would carry