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In similar studies, linagliptin has exhibited promising anti-inflammatory activity against acetic acid-induced colitis through the stimulation of the AMPK/SIRT1/PGC-1α pathway, as well as the inhibition of the JAK2/STAT3 signaling pathway, which may partly be mediated through AMPK activation (133)

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doi: 10.3892/or_00000762

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